Transcatheter aortic valve implantation (TAVI) is an effective and reliable method in the treatment of patients with serious aortic stenosis who are at high risk or inconvenient for surgery. Nevertheless, various procedure-related complications may develop. One of these complications is the obstruction of the ostial left main coronary artery (LMCA) due to calcification, native valve cusp, or bioprosthesis valve. It is difficult to treat LMCA obstruction and potentially it ends up catastrophically. Therefore, the aim must be to prevent LMCA obstruction. This article presents an 85-year-old female patient in whom acute LMCA obstruction was prevented by noticing that native valve calcification would obstruct LMCA during TAVI. To our knowledge, the effective method we used to prevent LMCA obstruction has not been reported in the literature.