Spiny Keratoderma Preceding Idiopathic Pulmonary Fibrosis: A Possible Clinical Association İdiyopatik Pulmoner Fibrozisten Önce Gelişen Dikenli Keratoderma: Olası Bir Klinik İlişki


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Dural M., Hamzaçebi F., Aydin M., KIRATLI NALBANT E.

Turkiye Klinikleri Dermatoloji, cilt.36, sa.2, ss.109-112, 2026 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2026
  • Doi Numarası: 10.5336/dermato.2025-113970
  • Dergi Adı: Turkiye Klinikleri Dermatoloji
  • Derginin Tarandığı İndeksler: Scopus, EMBASE, Academic Search Ultimate (EBSCO)
  • Sayfa Sayıları: ss.109-112
  • Anahtar Kelimeler: idiopathic pulmonary fibrosis, orthokeratosis, palmoplantar keratoderma, paraneoplastic dermatoses, Spiny keratoderma
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Music box spiny keratoderma is a rare hyperkeratotic disorder affecting the palms and soles, which may present in familial or sporadic forms. Familial cases are typically observed at younger ages, whereas sporadic cases are more frequently seen in older patients. Sporadic cases of spiny keratoderma may be associated with underlying malignancies and systemic diseases. Therefore, a comprehensive systemic evaluation should be performed in all patients with spiny keratoderma. In this report, we present a newly diagnosed case of acquired spiny keratoderma. Although acquired spiny keratoderma has been associated with idiopathic pulmonary fibrosis, the patient’s cutaneous lesions developed 2 years before the diagnosis of idiopathic pulmonary fibrosis. With this case, we aim to highlight the potential coexistence or sequential development of idiopathic pulmonary fibrosis in patients with spiny keratoderma.