This paper examines the role of financial development on entrepreneurship by employing panel data estimation methods for 17 emerging markets economies over the period 2004-2009. The financial development indicators, the impact of institutional factors and economic conditions on entrepreneurship will be empirically investigated in the analysis. In order to determine the linkages among the variables, two different measures for financial development and three institutional factors will be utilized in the analysis. Empirical findings indicate that while financial development and per capita income level have significantly and positively affected on entrepreneurship as theoretically expected, inflation rate has had negatively and significantly influencing entrepreneurship. Additionally, the effects of control of corruption and political stability, as institutional factors, on entrepreneurship are positive but insignificant.