Anakinra use during pregnancy: Report of a case with Familial Mediterranean Fever and infertility.

Ilgen U., Kucuksahin O.

European journal of rheumatology, vol.4, no.1, pp.66-67, 2017 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.5152/eurjrheum.2017.16075
  • Title of Journal : European journal of rheumatology
  • Page Numbers: pp.66-67


Familial Mediterranean fever (FMF), affecting people of Mediterranean origin, is an endemic and sometimes problematic disease because of colchicine resistance/intolerance, with relative lack of treatment alternatives, and disease-or treatment-related issues, such as subfertility. Anakinra, being a rational and effective treatment alternative, has no conclusive human pregnancy data. Here we report a case of FMF with infertility who became pregnant with in vitro fertilization (IVF) under treatment with anakinra, along with the pregnancy outcome.