Research Information System
International Journal of Clinical and Experimental Medicine, vol.13, no.1, pp.208-215, 2020 (Journal Indexed in SCI Expanded)
Although diabetes has been postulated as a risk factor for peri-implantitis, research on this subject has
been very limited. The purpose of this study was to evaluate the microbiological profiles in peri-implant sites and
the implant-abutment interface in diabetic and healthy implant recipients. The same root-form implant was used
in all the participants. 360 samples were collected at 4 different time points (2, 14, 30, and 90 days after surgery)
from 2 different locations (the peri-implant site and the implant-abutment interface) in triplicate. In the collected
samples, 4 pathogens associated with both periodontitis and peri-implantitis were counted using quantitative polymerase chain reactions. At the peri-implant sites, no statistical differences in the number of the investigated species were observed between the healthy and diabetic patients at any time point. The number of bacteria in the
implant-abutment interface increased with the implantation time. However, no significant difference was observed
between the healthy and diabetic patients at the implant-abutment interface. The profiles of the major pathogens
in the peri-implant site and the implant-abutment interface were not affected by diabetes. These findings are in accordance with previous studies.