COVID-19 infection may trigger SLE disease: A case report


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Atalar E., Maraş Y., SÜNGÜ N., Köksal Cevher Ş., Keleş M., Polat B.

Journal of Experimental and Clinical Medicine (Turkey), vol.39, no.3, pp.901-903, 2022 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.52142/omujecm.39.3.57
  • Journal Name: Journal of Experimental and Clinical Medicine (Turkey)
  • Journal Indexes: Scopus, Academic Search Premier, EMBASE
  • Page Numbers: pp.901-903
  • Keywords: antibodies, autoimmune diseases, COVID-19, lupus erythematosus, systemic
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

© 2022 Ondokuz Mayis Universitesi. All rights reserved.Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various body organs, especially the skin, joints, hematopoietic system, kidneys and central nervous system. The signs and symptoms occur depending on the inflammation in the affected tissues. Although many factors are responsible for its aetiology, it is known that some viruses such as Epstein Bar virus may also cause this disease by triggering autoimmunity. Recent studies have revealed that the immune system could be activated due to coronavirus infections and that some autoantibodies could be observed in the blood. A small number of SLE cases activated by COVID infection have been reported in the literature. The present study presented and discussed with the information in the literature a 20-year-old patient with COVID infection, diagnosed with SLE with renal involvement according to EULAR/ACR 2019 criteria by considering histopathological and immunofluorescence findings.