An ancient plant Lawsonia inermis (henna): Determination of in vitro antifungal activity against dermatophytes species


Gozubuyuk G., AKTAŞ E., YİGİT N.

Journal of Medical Mycology, cilt.24, sa.4, ss.313-318, 2014 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.mycmed.2014.07.002
  • Dergi Adı: Journal of Medical Mycology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.313-318
  • Anahtar Kelimeler: Antifungal activity, Dermatophytes, Henna paste
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

World is endowed with a rich wealth of medicinal plants. There is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. Medicinal plants have been used to cure a number of diseases. The ancient plant Lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer effect and possible anti-sweating properties. In this study, we investigated antifungal activity of L.inermis against clinical dermatophytes species. This study was carried out using 70 clinical isolates of dermatophytes representing six different species; 44 Trichophyton rubrum, 8 Trichophyton mentagrophytes, 6 Microsporum canis, 6 Trichophyton tonsurans, 4 Epidermophyton floccosum, and 2 Trichophyton violaceum. The antifungal activity of L.inermis (henna) was determined by agar diffusion method and henna was used as paste form. Henna paste showed the high antifungal activity against all dermatophytes species (20 to 50. mm inhibition zone).