A SCORING INDEX FOR PREDICTING THYROID MALIGNANCIES
Ankara Medical Journal, cilt.23, sa.2, ss.222-234, 2023 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 2
- Basım Tarihi: 2023
- Doi Numarası: 10.5505/amj.2023.88614
- Dergi Adı: Ankara Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.222-234
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Objectives: We evaluated ultrasonography (US) features of thyroid nodules ≤ 1 cm and > 1 cm and determined the features that might predict malignancy; we also aimed to develop a new scoring system considering US features to avoid unnecessary fine-needle aspiration biopsy (FNAB), particularly for sub-centimeter nodules. Materials and Methods: We retrospectively evaluated 2233 nodules of 1118 patients who underwent thyroidectomy. US features predictive for malignant histopathology were evaluated by multivariate logistic regression analysis. A US index score was calculated for each nodule considering these features. Results: 337 (15.11%) nodules were ≤1 cm, and 1896 (84.89%) were > 1 cm. In total, 173 (51.33%) of the ≤1 cm nodules were histopathologically benign, and 164 (48.67%) were malignant. Anteroposterior/transverse diameter (AP/T) ≥1, microcalcifications, macrocalcifications, and hypoechoic patterns were significantly more frequent in ≤1 cm malignant compared with benign nodules. Microcalcification, macrocalcification, hypoechoic and iso-hypoechoic patterns, and solid texture were significantly higher in the malignant than the benign group in > 1 cm nodules. The best cut-off of US index scores for discrimination of benign and malignant nodules were > 2 and > 4 for ≤1 cm and > 1 cm nodules, respectively. Conclusion: Our US scoring system may help clinicians and surgeons to select nodules for FNAB more accurately, particularly those sub-centimeter in size.