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European Journal of Gastroenterology and Hepatology, vol.37, no.6, pp.710-716, 2025 (SCI-Expanded)
Background and aim We aimed to compare two main existing scores, the Bowel Ultrasound Score (BUSS) and the International Bowel Ultrasound Segmental Activity Score (IBUS-SAS) to predict simplified endoscopic activity score for Crohn’s disease (SES-CD). Methods A cross-sectional study was conducted to evaluate the disease activity in Crohn’s disease (CD) patients with ileal involvement between November 2019 and February 2024. Endoscopic remission for CD was accepted as SES-CD ≤2. Results A total of 56 adult patients with CD (male: 38, 68%, median age: 40.5 years) were included in the study, the median duration of the disease was 8.4 years. The cutoff value for BUSS to determine endoscopic remission was 3.9, whereas the cutoff value for IBUS-SAS to establish endoscopic remission was 24.4. BUSS and SES-CD had a strong positive correlation (P < 0.001), BUSS and IBUS-SAS had a high positive correlation (P < 0.001), and BUSS and C-reactive protein had a slightly positive correlation (P < 0.001). Conclusion This study revealed that the cutoff values for BUSS and IBUS-SAS in CD patients with endoscopic remission were 3.9 and 24.4, respectively. Furthermore, it was demonstrated that BUSS and IBUS-SAS highly correlate with endoscopic activity in the real-world cohort.