Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Prpximal and Distal Colon


Bernardo D., Durant L., Mann E. R. , Bassity E., Montalvillo E., Man R., ...Daha Fazla

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, cilt.2, ss.22-44, 2016 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 2 Konu: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jcmgh.2015.08.006
  • Dergi Adı: CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
  • Sayfa Sayıları: ss.22-44

Özet

BACKGROUND & AIMS: Most knowledge about gastrointestinal (GO-tract dendritic cells (DC) relies on murine studies where CD103(+) DC specialize in generating immune tolerance with the functionality of CD11B(+/-) subsets being unclear. Information about human GI-DC is scarce, especially regarding regional specifications. Here, we characterized human DC properties throughout the human colon.