Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Prpximal and Distal Colon

Bernardo, David; Durant, Lydia; Mann, Elizabeth; Bassity, Elizabeth; Montalvillo, Enrique; Man, Ripple; Vora, Rakesh; Reddi, Durga; BAYIROĞLU, FAHRİ; Fernandez-Salazar, Luis; English, Nick; Peake, Simon; Landy, Jon; Lee, Gui; Malietzis, George; Siaw, Yi; Murugananthan, Aravinth; Hendy, Phil; Sanchez-Recio, Eva; Phillips, Robin; Garrote, Jose; Scott, Paul; Parkhil, Julian; Paulsen, Malte; Hart, Ailsa; Al-Hassi, Hafid; Arranz, Eduardo; Walker, Alan; Carding, Simon; Knight, Stella

doi:10.1016/j.jcmgh.2015.08.006

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Prpximal and Distal Colon

Bernardo D., Durant L., Mann E. R., Bassity E., Montalvillo E., Man R., ...Daha Fazla

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, cilt.2, sa.1, ss.22-44, 2016 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 2 Sayı: 1
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.jcmgh.2015.08.006
Dergi Adı: CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.22-44
Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

BACKGROUND & AIMS: Most knowledge about gastrointestinal (GO-tract dendritic cells (DC) relies on murine studies where CD103(+) DC specialize in generating immune tolerance with the functionality of CD11B(+/-) subsets being unclear. Information about human GI-DC is scarce, especially regarding regional specifications. Here, we characterized human DC properties throughout the human colon.