Clinical characteristics of 75 pandemic H1N1 infuenza patients from Turkey; risk factors for fatality
Turkish Journal of Medical Sciences, cilt.45, sa.3, ss.562-567, 2015 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 3
- Basım Tarihi: 2015
- Doi Numarası: 10.3906/sag-1401-111
- Dergi Adı: Turkish Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.562-567
- Anahtar Kelimeler: D-dimer, H1N1, Pneumonia, Pneumonia severity index
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır
Özet
Background/aim: The 2009 infuenza A (H1N1) pandemic caused mild to severe illnesses and led to death in some cases. In this study, we aimed to evaluate the relationship between the serum D-dimer levels, CURB-65 scores, and the severity of pneumonia among patients with H1N1 infections. Materials and methods: Sixty-eight patients who had probable H1N1 infections were evaluated by clinical, radiological, and laboratory methods. The H1N1 strain was specified by reverse transcription-polymerase chain reaction. Of 55 patients diagnosed with pneumonia, 18 exhibited H1N1 positivity and 37 patients did not. Results: CURB-65 scores of pneumonia patients with H1N1 (group 1) were higher than those of patients without H1N1 (group 2) (P = 0.02). The D-dimer levels of group 1were higher than those of group 2 (P = 0.001). Moreover, there was a positive correlation between D-dimer levels and CURB-65 scores in patients with H1N1-associated pneumonia (P = 0.001; r = 0.89). Conclusion: Increased D-dimer levels were observed in pneumonia patients with H1N1 infection, which predicted the severity of pneumonia.