Mechanical heart valve thrombosis in two pregnant patients followed up with low-molecular weight heparin therapy: A case report Iki gebe hastada gelisen mekanik kalp kapagi trombozunun düsük molekül agirlikli heparin tedavisi ile takibi: Olgu sunumu

HIDIROĞLU M., Küçüker A., Uçaroǧlu E. R., Kunt A., Çetin L., ŞENER E.

Turkish Journal of Thoracic and Cardiovascular Surgery, vol.20, no.3, pp.611-614, 2012 (SCI-Expanded, Scopus, TRDizin) identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.5606/tgkdc.dergisi.2012.117
  • Journal Name: Turkish Journal of Thoracic and Cardiovascular Surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.611-614
  • Keywords: Pregnancy, Prosthetic heart valves, Thrombosis
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

Life-long anticoagulation therapy is mandatory for patients with mechanical heart valves in order to prevent thromboembolic events. However, controversy still exists concerning which anticoagulant therapy protocol is best for pregnant patients with mechanical heart valves. In this article, we present two pregnant cases of mechanical heart valve thrombosis who were followed up with low-molecular weight heparin (LMWH) therapy. The patients, who were switched from anticoagulants to LMWH to prevent fetal side effects during pregnancy, underwent emergency surgery due to mechanical heart valve thrombosis in the 10th w eek a nd s ixth m onth o f pregnancy, respectively. Although fetal and baby loss occurred, the patients recovered in the postoperative period and were discharged uneventfully.