Mechanical heart valve thrombosis in two pregnant patients followed up with low-molecular weight heparin therapy: A case report Iki gebe hastada gelisen mekanik kalp kapagi trombozunun düsük molekül agirlikli heparin tedavisi ile takibi: Olgu sunumu
Turkish Journal of Thoracic and Cardiovascular Surgery, cilt.20, sa.3, ss.611-614, 2012 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 3
- Basım Tarihi: 2012
- Doi Numarası: 10.5606/tgkdc.dergisi.2012.117
- Dergi Adı: Turkish Journal of Thoracic and Cardiovascular Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.611-614
- Anahtar Kelimeler: Pregnancy, Prosthetic heart valves, Thrombosis
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Life-long anticoagulation therapy is mandatory for patients with mechanical heart valves in order to prevent thromboembolic events. However, controversy still exists concerning which anticoagulant therapy protocol is best for pregnant patients with mechanical heart valves. In this article, we present two pregnant cases of mechanical heart valve thrombosis who were followed up with low-molecular weight heparin (LMWH) therapy. The patients, who were switched from anticoagulants to LMWH to prevent fetal side effects during pregnancy, underwent emergency surgery due to mechanical heart valve thrombosis in the 10th w eek a nd s ixth m onth o f pregnancy, respectively. Although fetal and baby loss occurred, the patients recovered in the postoperative period and were discharged uneventfully.