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Turkiye Klinikleri Journal of Medical Sciences, vol.28, no.1, pp.24-29, 2008 (Scopus)
Objective: Formerly the treatment of the primer hyperparathyroidism (pHPT) was bilateral neck exploration, the identification of all parathyroid glands and the excision of the hyperplastic glands; however, recently with the aid of localization studies, focal exploration with unilateral surgical approach has been accepted. The aim of this study was to determine if the localization studies were adequate and to review the results of the patients we operated previously. Material and Methods: Fourteen patients who were operated for primer hyperparathyroidism were reviewed retrospectively. Localization studies were made by USG and parathyroid scintigraphy. Results: Ten (71.42%) out of 14 patients were females and 4 (28.57%) were males. The age of the patients ranged between 22 and 71; the mean age was 45.2. Only focal exploration and parathyroid adenom excision was carried out in 4 patients (28.57%) who had no thyroid pathologies. Ten patients (71.42%) who had thyroid pathologies underwent thyroidectomy. Blood calcium and parathormone values were decreased on postoperative day one in all patients but one (7.14%) whose adenoma excision was not successful. In three patients (21.42%) blood calcium levels were decreased and the excision of the adenom was confirmed histopathologicaly but the parathormone levels did not return to normal levels. Conclusion: In parathyroid adenomas, if USG and sestamibi scintigraphy points out the same localization focal exploration with unilateral surgical approach is adequate for the excision of the pathologic gland. However, in persistent and recurrent cases, visualization techniques like SPECT, sestamibi scintigraphy, computed tomography (CT) and magnetic resonance imaging (MRI) are required. Copyright © 2008 by Türkiye Klinikleri.