Age-related changes in biomechanical parameters of the cornea and intraocular pressure in a healthy Turkish population
Turkish Journal of Medical Sciences, cilt.44, sa.4, ss.687-690, 2014 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.3906/sag-1303-98
- Dergi Adı: Turkish Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.687-690
- Anahtar Kelimeler: Corneal biomechanics, Corneal hysteresis, Corneal resistance factor, Intraocular pressure, Ocular response analyzer
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır
Özet
Background/aim: To investigate age-related changes in intraocular pressure (IOP) and biomechanical parameters of the cornea in healthy subjects. Materials and methods: There were 404 healthy subjects included prospectively in this study. Te subjects were divided into 3 groups (Group 1: 93 subjects aged <18, Group 2: 189 subjects aged between 18 and 59, and Group 3: 122 subjects aged ≥60). Corneal compensated IOP (IOPcc), Goldmann correlated IOP (IOPg), corneal hysteresis (CH), and corneal resistance factor (CRF) were measured by the Ocular Response Analyzer. Results: When all the study groups were evaluated, a moderately significant negative correlation was found between age and CH and between age and CRF (Spearman's rho = -0.372 and -0.353, respectively; P < 0.0001 for both correlations). There were significant age-related differences among the 3 groups in terms of IOPg, CH, CRF, and central corneal thickness (P = 0.002, P = 0.000, P = 0.000, P = 0.006). There was no confirmation of any difference of IOPcc among the groups (P = 0.427). Conclusion: Te mean values of IOPg, CH, and CRF were lower than the other parameters in Group 3 but no significant differences were determined in IOPcc values in the age groups. © TÜBİTAK.