Migraine and angiotensin-converting enzyme association in Turkish patients


Cakmak E. A., Cataloluk O., YOLDAŞ T. K., Arslan A., Herken H., Barlas O., ...More

Pain Clinic, vol.15, no.4, pp.473-477, 2003 (Scopus)

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1163/156856903770196881
  • Journal Name: Pain Clinic
  • Journal Indexes: Scopus
  • Page Numbers: pp.473-477
  • Keywords: ACE, Genetics, Migraine, PCR
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

Although there are an increasing number of publications claiming involvement of the ACE I/D polymorphism in mood disorders, none of them has been able to show any linkage between allele and genotypical distributions and psychiatric disorders. We investigated the possibility of association between ACE I/D polymorphism and migraine in 200 migraineurs and 231 control subjects of Turkish origin. No association was found between ACE I/D polymorphism and migraine. However, the results of our study suggested that the DD genotype is more frequent in men than in women.