Research Information System
The Internet Journal of Gynecology and Obstetrics, vol.8, no.1, pp.1-5, 2007 (Refereed Journals of Other Institutions)
Probable clinical and microbial associations of genital mycoplasmas were investigated. Archive records of 290 female patients
with Mycoplasma hominis and Ureaplasma urealyticum were reviewed. A strong association was present between Mycoplasma
hominis and bacterial vaginosis (BV) (OR: 4.8; 95% CI: 2.65-8.69) and absence of normal vaginal flora (NVF) (OR: 3.08; 95%
CI: 1.76-5.39). Ureaplasma urealyticum was associated with BV (OR: 4.419; 95% CI: 2.43-8.03, p<0.010), weakly associated
with candida growth (OR: 1.84; 95% CI: 1.02-3.33), leukocyte presence in smear (leukocyte/epithelial cells>1) (p=0.045) and
contraceptive methods used (p=0.043). Detection of the two agents together was rather associated with BV (OR: 3.32; 95% CI:
1.82-6.04) and weakly with absence of NVF (OR: 2.15; 95% CI: 1.19-3.89). In conclusion, although causative agent of BV is still
unclear, Mycoplasma hominis and Ureaplasma urealyticum alone or together have a significant co-incidence with BV and
absence of normal vaginal flora.