TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, vol.39, no.2, pp.63-71, 2011 (Refereed Journals of Other Institutions)
Aim: The aim of this study is to compare efficacy of two skin disinfectants; 2 % 2- phenoxyethanol-0.1 % octenidin and 10 % povidon iodine; for the prevention of epidural catheter tip contamination. Materials and Methods: After obtaining approval and informed consent of the Ethics Committee, a total of 100 ASA I-II patients aged 18-65 years undergoing lower extremity surgery with similar antibiotic prophylaxis and no contraindication for epidural anesthesia and postoperative epidural analgesia were enrolled in the study. The patients were randomized into 2 equal groups according to use of antiseptic solution for skin disinfection before epidural anesthesia. Skin disinfection was performed with 2 % 2-phenoxyethanol-0.1 % octenidin in Group I (n=50) and 10 % povidon iodine in Group II (n=50). Pre- and postoperative total blood count, fever, signs of postoperative local skin infection were recorded. Catheters were removed at 48 hours and their distal tips were cultured. Results: The two groups were similar with respect to characteristics of patients. Postoperative mean body temperatures of patients in Group II were significantly higher than the ones in Group I (p<0.01). In Group II, 6 cultures of catheter tips yielded microorganisms. The bacterial species isolated were methicillin sensitive S.aureus in 4, and methicillin resistant S.aureus in 2 cases. Conclusion: Our results suggest that the use of 2 % 2-phenoxyethanol-0.1 % octenidin rather than 10 % povidon iodine may be a better choice for the prevention of bacterial contamination with epidural catheter.