Effect of alprostadil on erythrocyte deformability in ischemia reperfusion injury

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Kara H., Ozer A., Arpaci H., Demirtas H., Comu F. M., Oktar G. L., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.8, pp.509-511, 2015 (SCI-Expanded) identifier identifier identifier


BACKGROUND: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. Protective effect of alprostadil on local and distant organ injury due to I/R has been well-documented but its effect on erythrocyte deformability needs further investigation. Our aim was to investigate the effect of alprostadil on erythrocyte deformability in infrarenal aorta of rats undergoing I/R.