The Ameliorative Effects of Pycnogenol (R) on Liver Ischemia-Reperfusion Injury in Rats
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.14, no.3, pp.257-263, 2017 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 14 Issue: 3
- Publication Date: 2017
- Doi Number: 10.4274/tjps.49369
- Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.257-263
- Ankara Yıldırım Beyazıt University Affiliated: Yes
Abstract
Objectives: Pycnogenol (R) (PYC (R)), a standardized extract from the bark of Pinus maritima, consists of different phenolic compounds. PYC (R) has shown to have protective effects on chronic diseases such as diabetes, asthma, cancer, and immune disorders. The aim of this study was to determine the effects of PYC (R) against the DNA damage and biochemical changes in blood, liver, and lung tissues of ischemia-reperfusion (IR)-induced Wistar albino rats.