Ideal timing of labor in terms of oxidative stress - which term period is best?
Turkish Journal of Biochemistry, cilt.49, sa.1, ss.77-81, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 49 Sayı: 1
- Basım Tarihi: 2024
- Doi Numarası: 10.1515/tjb-2023-0098
- Dergi Adı: Turkish Journal of Biochemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Food Science & Technology Abstracts, Directory of Open Access Journals
- Sayfa Sayıları: ss.77-81
- Anahtar Kelimeler: antioxidant, disulfide, oxidant, term pregnancy, thiol
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Objectives: To determine the ideal timing of labor for term pregnancies using oxidative stress determiners. Methods: A total of 150 low-risk pregnant women were divided into three groups according to gestational week periods: early term, full term, and late-term. Groups were matched in terms of age and body mass index. Thiol/disulfide homeostasis parameters were obtained from maternal blood samples at the beginning of the active phase and from cord blood immediately after delivery. Results: Maternal and fetal native and total thiol, which indicates antioxidant status, were found to be significantly higher in full terms (maternal 397.5 ± 78.8, 435.9 ± 84.5, and fetal 472.5 ± 78.4, 513.7 ± 89.2 respectively; for all parameters p<0.05). The maternal oxidant balance was not significantly different between the groups; 1st-minute APGAR scores were significantly correlated with maternal antioxidant levels (p=0.042; r=0.199). Conclusions: The highest level of antioxidants in thiol/disulfide homeostasis in full-term pregnancies can be explained by the mechanism that increases the antioxidant level of the mother, which works best in the period between 39 and 41 weeks of pregnancy.