Behcet's syndrome and relationship with the ratio of insulin-like growth factor-1 (IGF-1)/IGF-binding protein-3 (IGFBP-3)


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Dogan O., Unal E., KISA Ü., Aksoy N.

POSTEPY DERMATOLOGII I ALERGOLOGII, cilt.36, sa.3, ss.295-301, 2019 (SCI-Expanded, Scopus)

Özet

Introduction: Behcet's syndrome (BS) is a chronic inflammatory disease with unknown aetiology. Insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) have important metabolic properties such as anabolic, cytoprotective and anti-inflammatory effects. Circulating IGF-1 and IGF-1/IGFBP-3 concentrations are associated with adiposity and insulin resistance.