Association of matrix metalloproteinases and their tissue inhibitor with disease activity and development in spondyloarthropathy and inflammatory bowel disease


Elmas D., ŞAHİN A., Kucuksahin O. , Turkcapar N., TÖRÜNER M., ÇETİNKAYA H., ...Daha Fazla

Archives of Rheumatology, cilt.30, ss.191-197, 2015 (SCI Expanded İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 30 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5606/archrheumatol.2015.5064
  • Dergi Adı: Archives of Rheumatology
  • Sayfa Sayıları: ss.191-197

Özet

Objectives: This study aims to investigate whether clinical measures of disease activity and function in ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are associated with matrix metalloproteinase-3 (MMP-3), matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase -1 (TIMP-1), and if MMPs can be more useful than C-reactive protein and erythrocyte sedimentation rate in predicting disease activity in AS.