Association of matrix metalloproteinases and their tissue inhibitor with disease activity and development in spondyloarthropathy and inflammatory bowel disease


Elmas D., ŞAHİN A., Kucuksahin O. , Turkcapar N., TÖRÜNER M., ÇETİNKAYA H., ...More

Archives of Rheumatology, vol.30, no.3, pp.191-197, 2015 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5606/archrheumatol.2015.5064
  • Title of Journal : Archives of Rheumatology
  • Page Numbers: pp.191-197

Abstract

Objectives: This study aims to investigate whether clinical measures of disease activity and function in ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are associated with matrix metalloproteinase-3 (MMP-3), matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase -1 (TIMP-1), and if MMPs can be more useful than C-reactive protein and erythrocyte sedimentation rate in predicting disease activity in AS.