Analysis of paraoxonase-1 (PON1) gene polymorphisms in vitiligo


SEÇKİN H. Y. , KALKAN G. , Benli I., Butun I., Bas Y., TAKCI Z., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.40, no.5, pp.356-362, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1515/tjb-2015-0027
  • Title of Journal : TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Page Numbers: pp.356-362

Abstract

Objective: Vitiligo is a chronic autoimmune depigmentation disease, which is characterized by loss of function of the melanocytes in epidermis. Recent studies suggest that oxidant/antioxidant status plays important role in the pathogenesis of vitiligo. We aimed to investigate possible associations between vitiligo and PON1 M/L55 and PON Q192R gene polymorphisms in the Turkish community.