Analysis of paraoxonase-1 (PON1) gene polymorphisms in vitiligo

SEÇKİN H. Y., KALKAN G., Benli I., Butun I., Bas Y., TAKCI Z., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.40, sa.5, ss.356-362, 2015 (SCI-Expanded, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1515/tjb-2015-0027
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.356-362
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Objective: Vitiligo is a chronic autoimmune depigmentation disease, which is characterized by loss of function of the melanocytes in epidermis. Recent studies suggest that oxidant/antioxidant status plays important role in the pathogenesis of vitiligo. We aimed to investigate possible associations between vitiligo and PON1 M/L55 and PON Q192R gene polymorphisms in the Turkish community.