Growth factor membranes in treatment of multiple gingival recessions: a randomized clinical trial.

Tazegül K., Doğan Ş., Ballı U., Dede F. Ö., Tayman M. A.

Quintessence international (Berlin, Germany : 1985), cilt.53, sa.4, ss.288-297, 2022 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.3290/j.qi.b2407765
  • Dergi Adı: Quintessence international (Berlin, Germany : 1985)
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.288-297
  • Anahtar Kelimeler: concentrated growth factor, gingival recession, plastic surgery, platelet-rich fibrin, root coverage
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

OBJECTIVE: The aim of this study was to assess the clinical effects of concentrated growth factor (CGF) in combination with coronally advanced flap (CAF) compared with platelet rich fibrin (PRF)+CAF for the treatment of multiple adjacent gingival recessions (GRs). METHOD AND MATERIALS: 18 subjects with total of 76 Type I GRs in the maxilla were included. Recessions were randomly treated according to a split-mouth design by means of CGF+CAF (39 defects, CGF side), or PRF+CAF (37 defects, PRF side). Clinical outcomes were evaluated at 6 months. RESULTS: The mean root coverage was 86.32% and 80.86%, and complete root coverage was 61.53% (24/39) and 51.35% (19/37) for CGF side and PRF side, respectively, at 6 months. Statistically significant gains were observed in the terms of clinical attachment level, recession depth, keratinized gingiva width, gingival thickness, and recession width in the both sides at 6 months compared to baseline values; no statistically significant difference was observed in these parameters between the two sides at 6 months. CONCLUSIONS: According to results, the use of CGF+CAF was not superior to PRF+CAF in providing additional benefits in clinical parameters. Keratinized gingiva width and gingival thickness significantly increased with the use of CGF and PRF membranes together with CAF.