Association of Ugrp2 gene polymorphisms with adenoid hypertrophy in the pediatric population


Atilla M. H. , Ozdas S., Ozdas T., Bastimur S., Muz S. E. , Oz I., ...More

BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol.84, no.5, pp.599-607, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 84 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1016/j.bjorl.2017.07.004
  • Title of Journal : BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
  • Page Numbers: pp.599-607

Abstract

Introduction: Adenoid hypertrophy is a condition that presents itself as the chronic enlargement of adenoid tissues; it is frequently observed in the pediatric population. The Ugrp2 gene, a member of the secretoglobin superfamily, encodes a low-molecular weight protein that functions in the differentiation of upper airway epithelial cells. However, little is known about the association of Ugrp2 genetic variations with adenoid hypertrophy.