Patient-Level Mass Findings on Mammography and Ultrasonography in Ductal Carcinoma In Situ: Association with Invasive Carcinoma
Diagnostics, vol.16, no.13, 2026 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 16 Issue: 13
- Publication Date: 2026
- Doi Number: 10.3390/diagnostics16132062
- Journal Name: Diagnostics
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO)
- Keywords: breast imaging, ductal carcinoma in situ, invasive carcinoma, mammography, mass lesion, multimodal imaging, ultrasonography
- Ankara Yıldırım Beyazıt University Affiliated: Yes
Abstract
Background: Preoperative identification of invasive carcinoma in patients with ductal carcinoma in situ (DCIS) remains challenging. While individual imaging findings have been widely investigated, the significance of mass findings identified on both mammography and ultrasonography remains less clearly defined. Methods: This retrospective study included 125 patients with DCIS who underwent both mammography and ultrasonography (US). Imaging findings were categorized as no mass on either modality, mass detected on a single modality, or mass findings identified on both mammography and ultrasonography. Associations between imaging patterns and invasive carcinoma were evaluated using descriptive analyses. Results: The proportion of invasive carcinoma was highest among patients with mass findings identified on both mammography and ultrasonography. Invasive carcinoma was observed in 6 of 71 patients (8.5%) with no mass on either modality, 5 of 37 patients (13.5%) with a mass detected on a single modality, and 8 of 17 patients (47.1%) with mass findings identified on both mammography and ultrasonography. However, substantial overlap between imaging categories remained present. Conclusions: Mass findings identified on both mammography and ultrasonography were more frequently observed in DCIS cases with invasive carcinoma. However, substantial overlap between imaging categories remained present, limiting reliable distinction at the individual patient level.