EARLY SİDE EFFECTS AFTER COVID-19 VACCİNE İN CHİLDREN AND ADOLESCENTS WİTH PSYCHİATRİC DİSORDERS


Kafalı S., Tural Hesapçıoğlu S., Aydın Ayva D., Tuncer D., Ceylan M. F.

ICP 2022: 13th International Congress on Psychopharmacology & International Symposium on Child and Adolescent Psychopharmacology, Antalya, Türkiye, 9 - 12 Kasım 2022, ss.131-132, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Antalya
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.131-132
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

EARLY SİDE EFFECTS AFTER COVID-19 VACCİNE İN CHİLDREN AND ADOLESCENTS WİTH PSYCHİATRİC DİSORDERS

 

Seda Kafalı, Selma Tural Hesapçıoğlu, Dilan Aydın Ayva, Duygu Aslantaş, Mehmet Fatih Ceylan

Department of Child and Adolescent Psychiatry, Ankara Yildirim Beyazit University School of Medicine, Ankara, Turkey

 

Vaccines for COVID-19 have reduced the severity of the infection and prevented deaths. During the beginning of the vaccinations, the parents of antipsychotic-using children begin to ask if the vaccine was safe for their children. Thus, we aimed to investigate if the side effects of the COVID-19 vaccine in adolescents with a psychiatric disorder that have to use antipsychotics are different from those of healthy peers.

 

We prospectively followed up the post-vaccine short term side effects of 88 patients aged 12-18 years old, followed up in the child and adolescent psychiatry clinic for at least 3 months, and compared them to 88 age and gender-matched healthy controls. Of the patients, 80 (%) of them were vaccinated with BNT162b2 as the healthy control group, the rest were with CoronaVac. 76 Of the patients were vaccinated with second, 21 were with third doses. This was 83 second doses, 26 third doses for controls. 45.4% of the patient group was using antipsychotics.

Patients who described side effects on the fourth day were examined in the clinic and the examination was repeated on the seventh day. The most frequently reported reaction after the first Biotech dose in the first four days in the patients’ group was local pain (58.8%), fatigue (16.3%), redness (12.5%), and headache (11.3%) and after the first Sinovac dose in patients were local pain (75.0%), redness (25.0%), fatigue (25.0%) and there was no significant difference from the control group. There were no patients nor controls stating any side effects that still exist at day 7 after every 3 doses. When the vaccines’ side effects are analyzed through the patients with and without antipsychotic use, there was no statistical difference between the groups.

These results show that vaccines examined in this study are safe in the short term for the antipsychotic-using adolescents.

 

Keywords: SARS-CoV-2, COVID-19, vaccine, psychiatric disorders, antipyschotics