A case of severe erythema nodosum induced by methimazole

Emre S., Ozdemir D., Orhun S., Kalkan G., Sener S.

SAUDI PHARMACEUTICAL JOURNAL, cilt.25, sa.5, ss.813-815, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Konu: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.jsps.2016.11.003
  • Sayfa Sayıları: ss.813-815


Erythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli. Hypersensitivity reactions due to medications have been recognized as a cause of 3-10% of EN cases. Case reports of EN associated with the anti-thyroid drugs are quite rarely reported in the literature even if there is a common use of anti-thyroid drugs. We report an EN case due to methimazole. The complaints of patients arose immediately fifteen days after the beginning of methimazole treatment. To the best of our knowledge, this case report is the first of an erythema nodosum induced by methimazole. (C) 2016 The Authors. Production and hosting by Elsevier B. V. on behalf of King Saud University.