Allergic granulomatosis and angiitis in the absence of asthma and blood eosinophilia: A rare presentation of limited Churg-Strauss syndrome

Sevinc A., HASANOĞLU H. C., Gokirmak M., Yildirim Z., Baysal T., Mizrak B.

Rheumatology International, vol.24, no.5, pp.301-304, 2004 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1007/s00296-003-0412-2
  • Journal Name: Rheumatology International
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.301-304
  • Keywords: Asthma, Churg-Strauss syndrome, Eosinophilia
  • Ankara Yıldırım Beyazıt University Affiliated: No

Abstract

Allergic granulomatosis and angiitis, also known as Churg-Strauss syndrome (CSS), is an uncommon vasculitis of unknown etiology. We report a 21-year-old male patient with fatigue, dry cough, and progressive dyspnea. He had no history of asthma or eosinophilia. Thorax computed tomography showed bullous/cystic areas with thin walls in varying sizes (5-15 mm). Histopathological examination of the open lung biopsy revealed granulomatous infiltration with histiocytes and eosinophilic leukocytes. This extremely rare variant of CSS is discussed.