Serum Lipid Profiles, Relationship Between Paraoxonase/Arylesterase Activity and High-density Lipoprotein Levels in Patients with Migraine

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Eren Y., Dirik E. B., NEŞELİOĞLU S., EREL Ö.

TURKISH JOURNAL OF NEUROLOGY, vol.23, no.3, pp.117-121, 2017 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.4274/tnd.09216
  • Journal Name: TURKISH JOURNAL OF NEUROLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.117-121
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

Objective: Paraoxonase 1 (PON1) is associated with high-density lipoprotein (HDL) and inhibits low-density lipoprotein (LDL) oxidation. The antioxidant and antiatherogenic characteristics of HDL are attributed to this feature. The mechanisms defined in the vascular atherosclerotic process, such as inflammation, oxidative stress, and endothelial dysfunction, are also present in migraine pathophysiology. The association between hyperlipidemia and migraine has been described in various studies; however, different results have been reported. We aimed to evaluate the general lipid profiles and the relationship between PON1, arylesterase (ARE) activity, and HDL levels in patients with migraine.