Serum Lipid Profiles, Relationship Between Paraoxonase/Arylesterase Activity and High-density Lipoprotein Levels in Patients with Migraine


Eren Y., Dirik E. B. , NEŞELİOĞLU S. , EREL Ö.

TURKISH JOURNAL OF NEUROLOGY, cilt.23, ss.117-121, 2017 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 23 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tnd.09216
  • Dergi Adı: TURKISH JOURNAL OF NEUROLOGY
  • Sayfa Sayısı: ss.117-121

Özet

Objective: Paraoxonase 1 (PON1) is associated with high-density lipoprotein (HDL) and inhibits low-density lipoprotein (LDL) oxidation. The antioxidant and antiatherogenic characteristics of HDL are attributed to this feature. The mechanisms defined in the vascular atherosclerotic process, such as inflammation, oxidative stress, and endothelial dysfunction, are also present in migraine pathophysiology. The association between hyperlipidemia and migraine has been described in various studies; however, different results have been reported. We aimed to evaluate the general lipid profiles and the relationship between PON1, arylesterase (ARE) activity, and HDL levels in patients with migraine.