IGF-I and IGFBP-3 levels and their correlations with carcinoembryonic antigen in colorectal cancer patients
ALEXANDRIA JOURNAL OF MEDICINE, cilt.54, sa.1, ss.11-15, 2018 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 1
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.ajme.2017.02.001
- Dergi Adı: ALEXANDRIA JOURNAL OF MEDICINE
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.11-15
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Background: Colorectal cancer is one of the most frequently seen cancers worldwide. Currently, CEA is the most commonly used tumor marker in colorectal cancer. The changes in IGF/IGFBP equilibrium is also known to cause carcinogenesis. In this study, we aimed to monitor IGF-I/IGFBP-3 levels, the changes in IGF-I/IGFBP-3 ratio and correlations of these peptides with the common tumor marker CEA.