IGF-I and IGFBP-3 levels and their correlations with carcinoembryonic antigen in colorectal cancer patients


Yucel C. Y. , Erden G., YILMAZ F. M. , Sezer S., Calci E.

ALEXANDRIA JOURNAL OF MEDICINE, cilt.54, ss.11-15, 2018 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 54 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.ajme.2017.02.001
  • Dergi Adı: ALEXANDRIA JOURNAL OF MEDICINE
  • Sayfa Sayısı: ss.11-15

Özet

Background: Colorectal cancer is one of the most frequently seen cancers worldwide. Currently, CEA is the most commonly used tumor marker in colorectal cancer. The changes in IGF/IGFBP equilibrium is also known to cause carcinogenesis. In this study, we aimed to monitor IGF-I/IGFBP-3 levels, the changes in IGF-I/IGFBP-3 ratio and correlations of these peptides with the common tumor marker CEA.