Oral and dental findings in Fanconi's anemia

Açikgöz A., Özden F. O., Fisgin T., Açikgöz G., Duru F., Yarali N., ...Daha Fazla

Pediatric Hematology and Oncology, cilt.22, sa.6, ss.531-539, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/08880010591002413
  • Dergi Adı: Pediatric Hematology and Oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.531-539
  • Anahtar Kelimeler: Dental abnormality, Fanconi's anemia, Gingivitis, Oral lesions, Periodontitis
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

Fanconi's anemia is an autosomal recessive disorder characterized by progressive pancytopenia and congenital malformation of the skeleton. This study investigated the oral health status of 15 children with Fanconi's anemia, including oral lesions, gingival and periodontal status, and dental abnormalities. All children in the group were found, to have a tendency to develop tooth decay and were in need of dental treatment. Two had aggressive periodontitis. In one patient supernumerary teeth were found, while in another teeth were congenitally missing. The increased tendency toward periodontal disease in patients with Fanconi's anemia may be due not only to the anemia, leukopenia, and defective detoxification of oxygen radicals that are charactetistic of the disease itself, but also to medications applied, during intense immunosuppressive treatment, such as prednisolone. Copyright © Taylor and Francis Inc.