Other, pp.757-765, 2022
Cancer development and progresson are assocated wth oxdatve stress. Oxdatve stress can favor hgh concentratons of reactve oxygen speces (ROS), and free radcals are assocated wth
antoxdant metabolsm. e human enzyme paraoxonase (PON) contrbutes to antoxdant metabolsm and decreased antoxdant levels. s leads to a hgh-rsk factor for coronary heart
dsease. s revew focuses on specfc changes that a ect the DNA molecule, and sgnalng pathways, and regulate the varous cancers through the attracton of PON, an enzyme for degradng
lpd peroxdes wthn the cell as well as lpoprotens n the bloodstream.