A current and comprehensive review of cyclin-dependent kinase inhibitors for the treatment of metastatic breast cancer


Bilgin B., Sendur M. A. N. , Dede D. S. , Akinci M. B. , Yalcin B.

CURRENT MEDICAL RESEARCH AND OPINION, cilt.33, ss.1559-1569, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/03007995.2017.1348344
  • Dergi Adı: CURRENT MEDICAL RESEARCH AND OPINION
  • Sayfa Sayıları: ss.1559-1569

Özet

Background: Resistance to endocrine treatment generally occurs over time, especially in the metastatic stage. In this paper, we aimed to review the mechanisms of cyclin-dependent kinase (CDK) 4/6 inhibition and clinical usage of new agents in the light of recent literature updates.