Association of Van Wyk Grumbach and Debre Semelaigne Syndromes with Severe Hypothyroidism

Akman, Alkim; Tayfun, Meltem; Demirel, Fatma; Ucakturk, Seyit; Gungor, Ali

doi:10.1016/j.jpag.2015.03.004

Association of Van Wyk Grumbach and Debre Semelaigne Syndromes with Severe Hypothyroidism

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Akman A. O. , Tayfun M., Demirel F., Ucakturk S. A. , Gungor A.

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, vol.28, no.6, 2015 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 28 Issue: 6
Publication Date: 2015
Doi Number: 10.1016/j.jpag.2015.03.004
Title of Journal : JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY

Abstract

Background: Van Wyk Grumbach syndrome (VWGS) and Kocher-Debre Semelaigne syndrome (KDSS) are rare forms of pseudo-precocious puberty and myopathy in patients with longstanding untreated hypothyroidism. We present the case of an adolescent girl who developed pseudo-precocious puberty and myopathy caused by long-term untreated hypothyroidism.