Association of Van Wyk Grumbach and Debre Semelaigne Syndromes with Severe Hypothyroidism

Akman A. O., Tayfun M., Demirel F., Ucakturk S. A., Gungor A.

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, vol.28, no.6, 2015 (SCI-Expanded) identifier identifier identifier


Background: Van Wyk Grumbach syndrome (VWGS) and Kocher-Debre Semelaigne syndrome (KDSS) are rare forms of pseudo-precocious puberty and myopathy in patients with longstanding untreated hypothyroidism. We present the case of an adolescent girl who developed pseudo-precocious puberty and myopathy caused by long-term untreated hypothyroidism.