Unit cell analysis and characterization of three-dimensional two-phase tissue scaffolds


Gomez C., Demirci M. F., Sun W., Shokoufandeh A.

Proceedings of the 2005 IEEE 31st Annual Northeast Bioengineering Conference, Hoboken, NJ, Amerika Birleşik Devletleri, 2 - 03 Nisan 2005, ss.166-167, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Hoboken, NJ
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Sayfa Sayıları: ss.166-167
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

Three-dimensional (3D) porous tissue scaffolds are being engineered to promote cell attachment, cell proliferation and functioning heterogeneous tissue formation. A scaffold's structure and transport capabilities need to mimic cells' natural geometrical and architectural environment and will need to consistently provide a flux throughout the scaffold to deliver materials for growth and waste removal. This paper presents our work on establishing a connectivity characterization of designed unit cell tissue structures for surface alignment between units to insure both geometric connectivity and mass and fluid transport within a heterogeneous tissue scaffold to meet both structural and biological requirements for cell growth and tissue growth. To capture this information, skeletal representations of the unit cell structures have been utilized for subsequent assembly processes. © 2005 IEEE.