Relationship between oxidant and antioxidant activity in hyperemesis gravidarum
Journal of Maternal-Fetal and Neonatal Medicine, cilt.27, sa.8, ss.825-828, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 8
- Basım Tarihi: 2014
- Doi Numarası: 10.3109/14767058.2013.842549
- Dergi Adı: Journal of Maternal-Fetal and Neonatal Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.825-828
- Anahtar Kelimeler: Antioxidant activity, Hyperemesis gravidarum, Pregnancy
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
Objective: To evaluate oxidant and antioxidant activity in patients with hyperemesis gravidarum (HG) by using serum total antioxidant activity (TAO), total free sulfhydryl (-SH), ceruloplasmin and lipid hydroperoxide (LOOH) levels. Materials and methods: In a cross-sectional trial, blood samples were collected from patients with HG (n=25) and healthy pregnant women (n=25) as control group. Serum TAO activities, -SH levels and LOOH levels and ceruloplasmin levels were measured. Results: Serum TAO activity was found to be significantly lower (p=0.003) in patients with HG compared with controls. However, serum -SH levels, LOOH levels and ceruloplasmin levels did not change significantly in patients with HG compared to controls. Conclusion: Presence of oxidative stress in HG patients depends more on reduced antioxidant activities than increased oxidative stress. © 2014 Informa UK Ltd.