Relation Between Systemic Immune-Inflammation Index and Post PCI Bleeding Risk in STEMI Patients


Kalkan K., Akdi A., Tunca Ç., Özbebek Y. E., Özkaya İbiş A., Kıvrak A., ...More

Journal of updates in cardiovascular medicine, vol.12, no.4, pp.125-132, 2024 (Peer-Reviewed Journal) identifier

Abstract

Objectives: To investigate the relationship between the systemic immune-inflammation index (SII) and bleeding complications in ST-elevated myocardial infarction (STEMI) after percutaneous coronary intervention (pPCI). Materials and Methods: This retrospective study included 1778 patients who presented with STEMI and underwent pPCI. Patients were divided into two groups: those who developed bleeding and those who did not. The SII values and CRUSADE bleeding score were calculated. Results: In the group with bleeding complications, the ages were 62 (50-73), and 69.6% were male. Multivariate analysis identified age 1.031(1.015-1.048) - p<0.001, basal creatinine 1.789 (1.366-2.342) - p<0.001, SII 1.163 (1.028-1.315)- p=0.013 as significant predictors of bleeding complications. Conclusion: The easily calculated SII may help predict bleeding complications in STEMI patients undergoing pPCI.