The Prevalence of Dry Eye and Sjogren Syndrome in Patients with Migraine

Sarac O., Kosekahya P., Tasci Y. Y. , Keklikoglu H. D. , Deniz O., Erten Ş. , ...More

OCULAR IMMUNOLOGY AND INFLAMMATION, vol.25, no.3, pp.370-375, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.3109/09273948.2015.1132739
  • Page Numbers: pp.370-375


Purpose: To evaluate the presence of dry eye and primary Sjogren syndrome (SS) in patients with migraine.Methods: In total, 46 eyes of 46 patients with migraine (group 1) and 50 eyes of 50 healthy subjects (group 2) were included in this study. Detailed ophthalmologic, neurologic and rheumatologic examination were performed on all participants. Ocular surface disease index questionnaire, tear function tests, visual analog scale for pain, serologic analysis were also performed.Results: Dry eye symptoms and findings were significantly higher and more severe in group 1 when compared with group 2. Primary SS was not found in any of the participants. The migraine lifetime duration was negatively correlated with the tear function tests while it was positively correlated with the ocular surface disease index scores.Conclusions: Dry eye symptoms and findings are higher in migraine patients when compared with the healthy subjects without the presence of Sjogren syndrome.