Association of Thiol Disulfide Homeostasis with Childhood Asthma
JOURNAL OF PEDIATRIC BIOCHEMISTRY, cilt.6, sa.3, ss.152-155, 2016 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 3
- Basım Tarihi: 2016
- Doi Numarası: 10.1055/s-0036-1597607
- Dergi Adı: JOURNAL OF PEDIATRIC BIOCHEMISTRY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
- Sayfa Sayıları: ss.152-155
- Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet
Özet
The aim of this study is to evaluate the oxidative stress level in asthmatic children in terms of the disulfide/thiol ratio, to research the role the disulfide/thiol ratio plays in the pathogenesis of the malady, and to determine the usefulness of the disulfide/thiol ratio as an indicator of the oxidation stress situations in patients with asthma. We report that the disulfide/thiol ratio and disulfide levels were significantly higher in the asthmatic group than in the control group. All in all, high levels of disulfide/thiol ratios in asthmatic children are thought to play roles in the pathogenesis of the disease.