Effects of antiepileptic drugs on dynamic thiol/disulphide homeostasis in children with idiopathic epilepsy

ARHAN, EBRU; KURT, AYŞEGÜL; NEŞELİOĞLU, SALİM; Yerel, Ozcan; Ucar, Habibe; Aydin, Kursad; SERDAROĞLU, AYŞE

doi:10.1016/j.seizure.2018.12.019

Effects of antiepileptic drugs on dynamic thiol/disulphide homeostasis in children with idiopathic epilepsy

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ARHAN E., KURT A. N. Ç. , NEŞELİOĞLU S., Yerel O., Ucar H. K. , Aydin K., ...More

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.65, pp.89-93, 2019 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 65
Publication Date: 2019
Doi Number: 10.1016/j.seizure.2018.12.019
Title of Journal : SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Page Numbers: pp.89-93

Abstract

Purpose: Anti-epileptic drugs have been widely used in children with epilepsy. Although several studies have investigated the role of oxidative stress and the effects of antiepileptic drugs on several oxidative markers in epilepsy, adequate information is not available on this issue. This study aimed to investigate the changes in thiol disulphide homeostasis in children with epilepsy under two commonly prescribed AED monotherapies, carbamazepine and valproic acid.