Linezolid and dexamethasone experience in a serious case of listeria rhombencephalitis


Yılmaz P. Ö., Mutlu N. M., SERTÇELİK A., Baştuğ A., Doğu C., Kışlak S.

Journal of Infection and Public Health, cilt.9, sa.5, ss.670-674, 2016 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jiph.2015.12.018
  • Dergi Adı: Journal of Infection and Public Health
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.670-674
  • Anahtar Kelimeler: Dexamethasone, Linezolid, Listeria rhombencephalitis
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

Listeria rhombencephalitis is a rare cause of brain stem encephalitis. We report a case with a history of immunosupressive therapy due to Takayasu's arteritis that was treated with corticosteroids and linezolid for Listeria rhombencephalitis. A 63-year-old woman was admitted to the hospital with fever, headache, nausea, and vomiting. The patient's body temperature was 38 °C, and she had a stiff neck. Listeria monocytogenes was isolated from the cerebrospinal fluid (CSF), and penicillin G and gentamicin treatment was initiated. Linezolid and dexamethasone were added. Due to hematuria and thrombocytopenia, the linezolid was discontinued. In immunocompromised patients with CNS infections, Listeria rhombencephalitis should be suspected. Linezolid can be used in combination with dexamethasone.