Cord blood prolidase activity correlates with gestational age and birth weight


ÇITAK KURT A. N., Ustundag B., Akarsu S., Kurt A., Yilmaz E., Ocal C., ...Daha Fazla

Neonatology, cilt.94, sa.2, ss.110-112, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 94 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1159/000119720
  • Dergi Adı: Neonatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.110-112
  • Anahtar Kelimeler: Birth weight, Cord blood, Gestational age, Prolidase
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Background: Prolidase, a specific iminopeptidase involved in collagen turnover, is especially active in growing tissues. Objectives: To investigate the relationship between cord blood prolidase activity and both birth weight and gestational age. Methods: Cord blood was collected consecutively from 50 healthy newborns (35 term, 15 preterm). Prolidase activity was measured in the samples using standard methods. Results: Themean ± SD cord blood prolidase activity was 41.4 ± 6.9 U/l in term infants and 35.2 ± 8.0 U/l in preterm infants and these were significantly different (p < 0.01). There were positive correlations between cord blood prolidase and both birth weight (r = 0.533, p < 0.01) and gestational age (r = 0.806, p < 0.01). Conclusion: Cord blood prolidase activity may be a good indicator of fetal maturation and gestational age. Copyright © 2008 S. Karger AG.