Cord blood prolidase activity correlates with gestational age and birth weight

ÇITAK KURT A. N., Ustundag B., Akarsu S., Kurt A., Yilmaz E., Ocal C., ...More

Neonatology, vol.94, no.2, pp.110-112, 2008 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 94 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.1159/000119720
  • Journal Name: Neonatology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.110-112
  • Keywords: Birth weight, Cord blood, Gestational age, Prolidase
  • Ankara Yıldırım Beyazıt University Affiliated: Yes

Abstract

Background: Prolidase, a specific iminopeptidase involved in collagen turnover, is especially active in growing tissues. Objectives: To investigate the relationship between cord blood prolidase activity and both birth weight and gestational age. Methods: Cord blood was collected consecutively from 50 healthy newborns (35 term, 15 preterm). Prolidase activity was measured in the samples using standard methods. Results: Themean ± SD cord blood prolidase activity was 41.4 ± 6.9 U/l in term infants and 35.2 ± 8.0 U/l in preterm infants and these were significantly different (p < 0.01). There were positive correlations between cord blood prolidase and both birth weight (r = 0.533, p < 0.01) and gestational age (r = 0.806, p < 0.01). Conclusion: Cord blood prolidase activity may be a good indicator of fetal maturation and gestational age. Copyright © 2008 S. Karger AG.