© 2021 Turkish Physiotherapy Association. All rights reserved.Purpose: Recently, it has been stated that there is a relationship between primary dysmenorrhea (PD) and fuction and alignment of the musculoskeletal system. The aim of this study was to compare spinal posture and mobility in women with and without PD. Methods: Women with (PD group, n=23, age=20.91±2.02 years, body mass index [BMI]= 21.63±2.98 kg/m2), and without (Control group, n=22, age=20.18±1.22 years, BMI= 20.79±2.43 kg/m2) PD were included in the study. Menstrual symptoms of women were recorded. Menstrual pain intensity with Visual Analog Scale (VAS), spinal posture and mobility with Valedo®Shape spinal posture and mobility measurement device (Hocoma, Idiag GmbH, Fehraltorf, Switzerland) were evaluated. Results: Menstrual symptoms of groups were similar (p>0.05). The mean value of the menstrual pain intensity in the PD group was 6.54±1.60 cm. There was no difference between thoracic, lumbar, sacral-hip, and inclination angles in the sagittal and frontal planes of the groups (p>0.05). It was found that the sacrum-hip mobility in the sagittal plane (p=0.025) and the thoracic (p=0.010) and lumbar mobility (p=0.020) in the frontal plane in PD group were lower than control group. The other mobility parameters were similar between the groups (p>0.05). Conclusion: In PD group compared to control group, the spinal posture did not change; however, it was seen that the spinal mobility decreased. According to results, it may be important to take into account decreased spinal mobility in the evaluation and treatment approaches of the PD in clinics.