Non-Invasive Skin Imaging Techniques for Diagnosing and Monitoring Mycosis Fungoides: A Comprehensive Review


İsmail Mendi B., İşibol C., Sayegh A., Mendi B. A. R., Atak M. F., Farabi B.

Cancers, cilt.18, sa.18, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 18 Sayı: 18
  • Basım Tarihi: 2026
  • Doi Numarası: 10.3390/cancers18182998
  • Dergi Adı: Cancers
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, CINAHL, EMBASE, Academic Search Ultimate (EBSCO), Natural Science Collection (ProQuest), Biological Science Database (ProQuest), Biomedical Reference Collection: Corporate Edition (EBSCO)
  • Anahtar Kelimeler: cutaneous T-cell lymphoma, dermoscopy, mycosis fungoides, non-invasive imaging, optical coherence tomography
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Mycosis fungoides, the most common primary cutaneous T-cell lymphoma, presents notable diagnostic challenges. In its early stages, it may resemble inflammatory dermatoses both clinically and histologically, causing delays in diagnosis. These factors can lead to treatment delays, allowing the disease to progress and adversely affecting the patient’s quality of life. To address this issue, the use of skin imaging techniques like dermoscopy, reflectance confocal microscopy, optical coherence tomography, and high-frequency ultrasound has increased in recent years. These techniques assist in diagnosis and treatment monitoring, reducing unnecessary biopsies by guiding accurate sampling from the most relevant sites and improving staging accuracy. This review provides a thorough overview of non-invasive skin imaging methods employed in the diagnosis and management of mycosis fungoides.