High prevalence of lower extremity peripheral artery disease in type 2 diabetes patients with diabetic nephropathy and the role of netrin-1 levels

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Kor A., Baldane S., Ipekci S. H., Marakoglu K., Altinok A., Unlu A., ...Daha Fazla

Endocrine Abstracts, cilt.1, sa.1, ss.1-2, 2017 (Hakemli Dergi)

• Yayın Türü: Makale / Özet
• Cilt numarası: 1 Sayı: 1
• Basım Tarihi: 2017
• Doi Numarası: 10.1530/endoabs.49.gp96
• Dergi Adı: Endocrine Abstracts
• Sayfa Sayıları: ss.1-2
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Background: Netrin-1 is an early biomarker of acute kidney injury. Besides, recent

studies have showed that netrin-1 promotes angiogenesis; but its usefulness for

peripheral artery disease (PAD) in type 2 diabetes patients is unknown.This study aimed

at investigating whether netrin-1 levelsare increased in peripheral artery disease among

patients with type 2 diabetes and also investigating possible associationsbetween

diabetic nephropathy (DN) and PAD.

Material and Methods: This was a cross-sectional observational clinical study. This study

involved a total of 84 adults with type 2 DM, who underwent ABI (low ankle-brachial

index) measurement in an outpatient clinic. PAD was de