© 2021 John Wiley & Sons Ltd.In recent years, the rapid development in information technologies appears in the form of digitalization, all of the processes in the health domain. Among the state-of-art, virtual reality, artificial intelligence, and blockchain technologies are among the most mentioned. In addition, the exponential increase in data kept in the electronic environment causes traditional central applications to face new challenges. The most important of these are accountability, transparency, security, cost, and time efficiency. In this study, a model based on blockchain technologies has been proposed to increase the transparency, accountability, and security of multi-stakeholder shared medical data by using smart contracts (SCs). In the first part, there are briefly introduced the current situation of the health domain, blockchain technology, hyperledger fabric (HLF) and SCs. Afterward, in line with the latest technological developments, the studies carried out using the blockchain framework related to organ/tissue transplantation were examined. Lastly, the proposed framework was designed based on blockchain technologies for organ/tissue transplantation by using the HLF environment. The blockchain technology not only provides more visibility, more security, and better outcomes but also enables to store data securely and cheaply without allocating extra resources to a trusted authority. Thus, it can be ensured that the system is more transparent and more accountable.