Dynamic thiol-disulfide homeostasis is disturbed in patients with non-alcoholic fatty liver disease


Asil M., DERTLİ R., BIYIK M., Yolacan R., EREL Ö., NEŞELİOĞLU S., ...Daha Fazla

JOURNAL OF LABORATORY MEDICINE, cilt.42, ss.31-38, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1515/labmed-2017-0018
  • Dergi Adı: JOURNAL OF LABORATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.31-38
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

Background: Oxidative stress has been implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Plasma thiols are major defense mechanisms against oxidative stress and undergo oxidation to form disulfides under oxidative conditions. This study was conducted to investigate thiol-disulfide homeostasis in NAFLD patients.