Dynamic thiol-disulfide homeostasis is disturbed in patients with non-alcoholic fatty liver disease

Asil M., DERTLİ R., BIYIK M., Yolacan R., EREL Ö., NEŞELİOĞLU S., ...More

JOURNAL OF LABORATORY MEDICINE, vol.42, pp.31-38, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 42
  • Publication Date: 2018
  • Doi Number: 10.1515/labmed-2017-0018
  • Title of Journal : JOURNAL OF LABORATORY MEDICINE
  • Page Numbers: pp.31-38

Abstract

Background: Oxidative stress has been implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Plasma thiols are major defense mechanisms against oxidative stress and undergo oxidation to form disulfides under oxidative conditions. This study was conducted to investigate thiol-disulfide homeostasis in NAFLD patients.