Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis

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SÖNMEZ M. G., Kozanhan B., Deniz C. D., Iyisoy M. S., Kilinc M. T., Ecer G., ...Daha Fazla

INVESTIGATIVE AND CLINICAL UROLOGY, cilt.60, sa.4, ss.258-266, 2019 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 60 Sayı: 4
• Basım Tarihi: 2019
• Doi Numarası: 10.4111/icu.2019.60.4.258
• Dergi Adı: INVESTIGATIVE AND CLINICAL UROLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.258-266
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ankara Yıldırım Beyazıt Üniversitesi Adresli: Hayır

Özet

Purpose: A dynamic thiol/disulfide balance is pivotal in organizing anti-oxidant defense, detoxification, apoptosis, and enzyme activities, as well as transcription and cellular signal-transfer mechanisms. The connection between urolithiasis and oxidant/antioxidant status, which can be assessed through thiol-disulfide homeostasis (TDH), has not yet been examined. In this study, we evaluated the effects of TDH on the formation, size, and location of stones by examining the associations between TDH parameters and urolithiasis.