Dynamic thiol/disulfide homeostasis as a novel indicator of oxidative stress in patients with urolithiasis

SÖNMEZ M. G. , Kozanhan B., Deniz C. D. , Iyisoy M. S. , Kilinc M. T. , Ecer G., ...Daha Fazla

INVESTIGATIVE AND CLINICAL UROLOGY, cilt.60, sa.4, ss.258-266, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Konu: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4111/icu.2019.60.4.258
  • Sayfa Sayıları: ss.258-266


Purpose: A dynamic thiol/disulfide balance is pivotal in organizing anti-oxidant defense, detoxification, apoptosis, and enzyme activities, as well as transcription and cellular signal-transfer mechanisms. The connection between urolithiasis and oxidant/antioxidant status, which can be assessed through thiol-disulfide homeostasis (TDH), has not yet been examined. In this study, we evaluated the effects of TDH on the formation, size, and location of stones by examining the associations between TDH parameters and urolithiasis.