A Rare Cause of Hematuria in Children: Ebstein-Barr Virus Çocuklarda Hematürinin Nadir Bir Nedeni: Ebstein-Barr Virus
Cocuk Enfeksiyon Dergisi, vol.15, no.4, pp.240-243, 2021 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 15 Issue: 4
- Publication Date: 2021
- Doi Number: 10.5578/ced.20219617
- Journal Name: Cocuk Enfeksiyon Dergisi
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Page Numbers: pp.240-243
- Keywords: Epstein-Barr virus, Hematuria, Nephritis
- Ankara Yıldırım Beyazıt University Affiliated: Yes
Abstract
A 16.5-year-old male was admitted to the emergency department with fever, sore throat and hematuria. The patient’s body temperature was measured as 40oC, there was no edema and his blood pressure was normal. Oropharynx was hyperemic, there was jaundice on the skin and sclera, hepatosplenomegaly, and multiple lymph nodes up to 4 cm in both cervical chains. Laboratory studies revealed prominent lymphomonocytosis and Downey cells in peripheral blood smear. Liver enzymes and bilirubin levels were elevated, kidney functions were normal. Urinary examination revealed hematuria and non-nephrotic proteinuria. His urinary outflow was normal in follow up. Ultrasonography showed hepatosplenomegaly and an increase in renal parenchymal echogenicities. Epstein-Barr Virus viral capsid antigen immunoglobulin M was positive, polymerase chain reaction result was positive with 140.000 copies/µL. In the follow-up, steroid treatment was given due to persistent fever and rapid growth in lymph nodes, and then the fever did not recur. Macroscopic hematuria improved on the fourth day of his hospitalization, and at the third week of control, hematuria and proteinuria disappeared completely.