A Rare Cause of Hematuria in Children: Ebstein-Barr Virus Çocuklarda Hematürinin Nadir Bir Nedeni: Ebstein-Barr Virus


Yılmaz S., BAYHAN G. İ., KARBANCIOĞLU E. Y.

Cocuk Enfeksiyon Dergisi, cilt.15, sa.4, ss.240-243, 2021 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5578/ced.20219617
  • Dergi Adı: Cocuk Enfeksiyon Dergisi
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.240-243
  • Anahtar Kelimeler: Epstein-Barr virus, Hematuria, Nephritis
  • Ankara Yıldırım Beyazıt Üniversitesi Adresli: Evet

Özet

A 16.5-year-old male was admitted to the emergency department with fever, sore throat and hematuria. The patient’s body temperature was measured as 40oC, there was no edema and his blood pressure was normal. Oropharynx was hyperemic, there was jaundice on the skin and sclera, hepatosplenomegaly, and multiple lymph nodes up to 4 cm in both cervical chains. Laboratory studies revealed prominent lymphomonocytosis and Downey cells in peripheral blood smear. Liver enzymes and bilirubin levels were elevated, kidney functions were normal. Urinary examination revealed hematuria and non-nephrotic proteinuria. His urinary outflow was normal in follow up. Ultrasonography showed hepatosplenomegaly and an increase in renal parenchymal echogenicities. Epstein-Barr Virus viral capsid antigen immunoglobulin M was positive, polymerase chain reaction result was positive with 140.000 copies/µL. In the follow-up, steroid treatment was given due to persistent fever and rapid growth in lymph nodes, and then the fever did not recur. Macroscopic hematuria improved on the fourth day of his hospitalization, and at the third week of control, hematuria and proteinuria disappeared completely.